Instant Knockout is one of the most well-known and widely-used fat burner supplements on the market so we’d thought we’d put together an Instant Knockout Review to see if it is as effective as everyone says.

Originally created for MMA fighters looking to shred before a fight, it’s now available to gym-goers and athletes alike.

In this Instant Knockout review, we’ll take a look at the ingredients to assess how good this product really is.  By looking at the serving sizes, ingredients used, quality and research surrounding each element, we can get a good understanding of what you can expect from this ‘so-called’ fat burner.

One thing to keep in mind before reading on is that fat burner supplements have not been proven to influence weight loss. While the ingredients in the formula might show promise in research, we cannot guarantee results and they certainly shouldn’t be solely relied upon for weight loss.

They’re simply designed to support a healthy calorie-restricted diet and regular exercise. Without these two things, you will not lose weight.

With the overview out of the way, let’s take a look at what Instant Knockout can do.

What are the benefits of taking Instant Knockout?

The ingredients within this supplement should offer a range of benefits that may be able to support you with your weight loss efforts.

With regular use of this product, you could expect the following:

Should help you burn calories

Several ingredients within this formula have been proven to boost the metabolism due to their thermogenic properties when served at specific levels. The combination of these elements may help to increase calorie burn.

Suppress your appetite

One element within this supplement (Glucomannan) is a proven appetite suppressant which has been linked to weight loss. While the amount used in Instant Knockout isn’t as high as those used in the studies, compared to other similar supplements, it still offers a very generous serving.

Maintain high energy levels

Instant Knockout uses caffeine to help you stay energized and active during a low energy diet. This may help you to exercise more, which could influence further weight loss.

Is it safe?

A key part of this Instant Knockout Review, or any review for that matter is to determine if the products you’re going to take are safe. The good news is that Instant Knockout uses natural ingredients and there have been very few reports of any side effects.

The main worry with this type of product is the caffeine content. Compared to other similar fat burners, it offers relatively low serving of the stimulant which is about the same as a weak cup of coffee in each capsule.

Nonetheless, to avoid any unwanted adverse symptoms, we recommend reducing your caffeine intake throughout the day. As it is a stimulant, we advise that you take your last capsule at least 5 hours before you go to bed, otherwise it could interfere with your sleep.

Instant Knockout also doesn’t contain any proprietary blends. This is refreshing to see and means that you can see exactly what you are putting in your body. Some companies use proprietary blends to hide low quality or ineffective ingredients to keep their production price low.

If there is any chance you could be pregnant avoid taking anything containing caffeine. Speak to your physician before buying a fat burner supplement.

Instant Knockout ingredients

This supplement utilises 10 natural ingredients like vitamins and plant extracts with the intention of helping you lose weight. After taking a closer look, we found a good amount of research behind each of these ingredients.

Take a look at the most important ingredients below.

Green tea extract

This ingredient can be found in most fat burners due to its thermogenic properties.

Research has linked its ability to raise the metabolism to weight loss on several occasions [1][2]. One study found that taking green tea every day helped to burn an additional 179 calories [2].

Another trial found that overweight women who used green tea extract supplements over 12-weeks lost significantly more weight than those who didn’t take it [3].

Cayenne Pepper Seeds

Another popular ingredient in fat burners, this ingredient contains a thermogenic compound called capsaicin. In a trial, researchers found that when participants were given cayenne pepper in their meal, their metabolism was significantly increased compared to those who didn’t have the spice in their food [4].


Extracted from the root of the Konjac plant, Glucomannan is a soluble fiber that expands slightly when in the stomach, which results in a feeling of fullness.

This has been linked to weight loss in short studies. In a five-week placebo trial, those who took glucomannan were shown to lose fat at a much higher rate than those who didn’t take it [5].

Caffeine Anhydrous

Caffeine is another proven thermogenic. When supplemented in trials, it was proven to enhance metabolism by around 11% [6] and specific at burning by 13% [7].

As it is a stimulant, it can also help you to feel more energized, which has been shown to increase physical performance during training [8].

Vitamin B6 & B12

These vitamins play a crucial role in a number of metabolism processes. It’s been shown to improve the way you process energy and help to prime your body for muscle growth [9][10].

Since they play such an important role in key fat burning processes, they may help to promote weight loss.

How to take Instant Knockout

The creators of Instant Knockout have advised that you take 4 capsules throughout the day to achieve the best results.

The ingredients used in Instant Knockout should be taken in a certain way to help achieve better results. According to research, the best time to take an appetite suppressant is around 90 minutes before a meal.

Therefore, we suggest you follow this pattern:

  • First capsule 30 minutes before breakfast
  • Second capsule 30 minutes before lunch
  • Third capsule at around mid-afternoon
  • Final capsule around 30 minutes before evening meal

Wash each capsule down with a large glass of water.

As is always the case with weight loss, consistency is key. To achieve the results you want, you’ll need to take Instant Knockout consistently as well as sticking to your diet and exercise plans.

Due to the caffeine content, we would advise that you do not take your last capsule any later than 5 hours before you go to bed.

How much does it cost?

We couldn’t do an Instant Knockout Review without taking a look at the cost. One bottle of Instant Knockout provides 120 capsules, which is enough for 30 days.

  • One bottle costs: $59/£35
  • Two bottles + FREE shipping: $118/£70
  • Three bottles + one FREE bottle + FREE shipping: $185/£110

If you decide Instant Knockout is the fat burner supplement for you, we suggest that you opt for the three-bottle bundle as you’ll save money and you’ll be covered by their 90-day guarantee. Weight loss doesn’t just happen overnight, so the larger bundle could be your best option in the long run.

Instant Knockout Reviews

With so many fat burner options to choose from, it’s always worth spending your time looking for reviews and testimonials for the products – luckily, with Instant Knockout being so well established, there are plenty available.

Straight off the bat we noticed how well received Instant Knockout was. We found numerous testimonials including impressive before and after pictures, with customers claiming the product helped them lose weight.

The product is endorsed by quite a few athletes, with one of the most popular recommendations coming from Diego Sanchez, an MMA fighter who whilst coming back from injury dropped 25lb in 4 weeks.

We did find some negative reviews of Instant Knockout, with customers not noticing any weight loss. As we’ve already advised, fat burners aren’t a magic pill, everyone’s body won’t react the same and it may take longer for people to see the effects.

You can view customer testimonials for Instant Knockout on the website.


Instant Knockout is backed by research, with high quality ingredients served at optimal doses – something that’s hard to find in the world of fat burner supplements.

Overall, we think this is a great supplement if you’re looking to buy a fat burner.

The quality of the product, bundled with the endorsements and testimonials that we found online means we give it a big thumbs up.

While the price is a little higher than the majority of similar supplements, we think it’s worth the additional cost.


  • Natural ingredients
  • Well-researched formula
  • Optimal doses
  • Low risk of side effects


  • Premium price
  • Can only buy direct

If you liked this Instant Knockout Review, be sure to check out our list of best fat burners for men!

References: 1. Rains TM, e. (2010). Antiobesity effects of green tea catechins: a mechanistic review. – PubMed – NCBI. [online] 2. Bérubé-Parent S, e. (2005). Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure… – PubMed – NCBI. [online] 3. Chen IJ, e. (2016). Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial. – PubMed – NCBI. [online] 4. Yoshioka, M et al. Effects of red-pepper diet on the energy metabolism in men. J Nutr Sci Vitaminol (Tokyo). 1995; 41(6): 647-56 5. Bjerketvedt GS, et al. Experiences with three different fiber supplements in weight reduction. Med Sci Monit. 2005 Jan 6. Acheson KJ, e. (1980). Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. – PubMed – NCBI. 7. Acheson KJ, e. (2004). Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? – PubMed – NCBI. [online] 8. Goldstein E, Ziegenfuss T, Kalman D et al. International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr. 2010;7(1):5. doi:10.1186/1550-2783-7-5 9. Zemel, MB et al. Effects of a Leucine and Pyridoxine-Containing Nutraceutical on Fat Oxidation, and Oxidative and Inflammatory Stress in Overweight and Obese Subjects. Nutrients. 2012; 4(6): 529-541 10.